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Microbes in Space

In light of an upcoming new era of human expansion in the universe, such as future space travel to Mars, the microbiome of the closed space environment needs to be examined thoroughly to identify the types of microorganisms that can accumulate in this unique environment, how long they persist and survive and their impact on human health and spacecraft infrastructure.

(208) Neuroprotective roles of fractalkine in multiple sclerosis: Characterization of novel humanized animal model

Multiple sclerosis (MS), an inflammatory demyelinating disease of the CNS is the leading cause of nontraumatic neurological disability in young adults. Immune mediated destruction of the myelin and oligodendrocytes are considered the primary pathology of MS, but progressive axonal loss is the major cause of neurological disability.

HDX and Imaging in the Core

Hydrogen-deuterium exchange (HDX) mass spectrometry and imaging mass spectrometry (IMS) are two cutting edge mass spectrometry techniques that are not frequently found in Core facilities. HDX-MS provides protein structure information and information on protein-protein interaction sites. IMS provides analyte (lipid, metabolites, drugs, and proteins) localization within tissue samples.